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1.
J Int Adv Otol ; 18(6): 465-470, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-36349666

RESUMO

BACKGROUND: The aim of this study was to assess the effect on speech perception and lack of hearing devices gain with surgical masks worn in hearing aid users. METHODS: This prospective cohort study enrolled consecutive patients between November 2020 and February 2021 in a tertiary care medical center from Spain. Fifty-five subjects have been included, 10 as control group, with normal hearing, and 45 patients with sensory-neural hearing loss and hearing aid users, ranging in age between 31 and 83 years old, and were recruited randomized in 4 months. Appropriate test was done previously to check adequate functioning from devices and suitable adaptation. Control group had no hearing impairment neither otologic disease. RESULTS: Disyllabic test in quiet get worse with face mask with a significant difference and stronger impact in noisy background. Age made no difference. Adding lipreading speech perception improved by 95.1 % for younger subjects (<50 years of age) and 91.2% for older subjects (>50 years of age). In the control sample, there was no differences in any condition. CONCLUSION: Despite advantages of wearing mask in preventing coronavirus disease 2019 spread, we must consider that they have also drawbacks for some groups like hearing aid users. In this research, we have not observed high frequencies perception decrease with surgical masks worn, but there was reduction in speech perception, most notably in hearing aids wearers in noisy environment.


Assuntos
COVID-19 , Auxiliares de Audição , Percepção da Fala , Humanos , Pré-Escolar , Criança , Idoso de 80 Anos ou mais , Máscaras , COVID-19/epidemiologia , Estudos Prospectivos , Audição
2.
J Clin Med ; 11(14)2022 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-35887693

RESUMO

New cochlear implant (CI) electrode arrays provide softer insertion dynamics; however, due to their high flexibility, the possibilities of fold-overs or intraoperative displacements must be taken into account. The position of each individual electrode can only be determined by using high-resolution computed tomography or cone-beam CT. The trans-impedance matrix test (TIM) is an electrophysiological method based on electric field imaging that can provide images of electrode position and electrode folding. OBJECTIVE: In this experimental research, we evaluated the result of TIM as a method of monitoring cochlear insertion for a precurved slim modiolar electrode array in fresh human temporal bones by analyzing the transimpedance matrix patterns and their correlation with electrode position using high-resolution computed tomography. MATERIAL AND METHODS: Sixteen slim modiolar electrode arrays were inserted into eight fresh Human Temporal Bones. Eight electrodes were inserted according to the correct methodology of insertion, and eight were intentionally folded over. After all insertions, a trans-impedance matrix analysis and a Cone Beam CT (CBCT) were performed in each temporal bone. RESULTS: If we correlated the TIM patterns with the radiological electrode position, we observed that better electrode intracochlear positions indicated more "homogeneous" TIM patterns (intracochlear voltage dropped monotonically as the distance between stimulation and recording contact increased, both toward the apex and toward the base). A correlation where fold-over was detected in the TIM results was found in all eight temporal bone radiological findings. CONCLUSIONS: Trans-Impedance Matrix patterns were correlated with the radiological CI electrode position. When a tip fold-over appeared, a matrix with a secondary ridge in addition to the primary ridge was observed in all cases. TIM can be an effective method in the control of electrode positioning.

3.
PLoS Comput Biol ; 18(5): e1010134, 2022 05.
Artigo em Inglês | MEDLINE | ID: mdl-35622861

RESUMO

There is a growing interest in biomedical engineering in developing procedures that provide accurate simulations of the neural response to electrical stimulus produced by implants. Moreover, recent research focuses on models that take into account individual patient characteristics. We present a phenomenological computational model that is customized with the patient's data provided by the electrically evoked compound action potential (ECAP) for simulating the neural response to electrical stimulus produced by the electrodes of cochlear implants (CIs). The model links the input currents of the electrodes to the simulated ECAP. Potentials and currents are calculated by solving the quasi-static approximation of the Maxwell equations with the finite element method (FEM). In ECAPs recording, an active electrode generates a current that elicits action potentials in the surrounding auditory nerve fibers (ANFs). The sum of these action potentials is registered by other nearby electrode. Our computational model emulates this phenomenon introducing a set of line current sources replacing the ANFs by a set of virtual neurons (VNs). To fit the ECAP amplitudes we assign a suitable weight to each VN related with the probability of an ANF to be excited. This probability is expressed by a cumulative beta distribution parameterized by two shape parameters that are calculated by means of a differential evolution algorithm (DE). Being the weights function of the current density, any change in the design of the CI affecting the current density produces changes in the weights and, therefore, in the simulated ECAP, which confers to our model a predictive capacity. The results of the validation with ECAP data from two patients are presented, achieving a satisfactory fit of the experimental data with those provided by the proposed computational model.


Assuntos
Implante Coclear , Implantes Cocleares , Potenciais de Ação/fisiologia , Implante Coclear/métodos , Nervo Coclear/fisiologia , Simulação por Computador , Estimulação Elétrica , Potenciais Evocados/fisiologia , Potenciais Evocados Auditivos/fisiologia , Humanos
4.
Audiol Neurootol ; 27(5): 347-355, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35306487

RESUMO

INTRODUCTION: Transimpedance measurements from cochlear implant electrodes have the potential to identify anomalous electrode array placement, such as tip fold-over (TFO) or fold-back, basal electrode kinking, or buckling. Analysing transimpedance may thus replace intraoperative or post-operative radiological imaging to detect any potential misplacements. A transimpedance algorithm was previously developed to detect deviations from a normal electrode position with the aim of intraoperatively detecting TFO. The algorithm had been calibrated on 35 forced, tip folded electrode arrays in six temporal bones to determine the threshold criterion required to achieve a sensitivity of 100%. Our primary objective here was to estimate the specificity of this TFO algorithm in patients, in a prospective study, for a series of electrode arrays shown to be normally inserted by post-operative imaging. METHODS: Intracochlear voltages were intraoperatively recorded for 157 ears, using Cochlear's Custom Sound™ EP 5 electrophysiological software (Cochlear Ltd., Sydney, NSW, Australia), for both Nucleus® CI512 and CI532 electrode arrays. The algorithm analysed the recorded 22 × 22 transimpedance matrix (TIM) and results were displayed as a heatmap intraoperatively, only visible to the technician in the operating theatre. After all clinical data were collected, the algorithm was evaluated on the bench. The algorithm measures the transimpedance gradients and corresponding phase angles (θ) throughout the TIM and calculates the gradient phase range. If this was greater than the predetermined threshold, the algorithm classified the electrode array insertion as having a TFO. RESULTS: Five ears had no intraoperative TIM and four anomalous matrices were identified from heatmaps and removed from the specificity analysis. Using the 148 remaining data sets (n = 103 CI532 and n = 45 CI512), the algorithm had an average specificity of 98.6% (95.80%-99.75%). CONCLUSION: The algorithm was found to be an effective screening tool for the identification of TFOs. Its specificity was within acceptable levels and resulted in a positive predictive value of 76%, with an estimated incidence of fold-over of 4% in perimodiolar arrays. This would mean 3 out of 4 cases flagged as a fold-over would be correctly identified by the algorithm, with the other being a false positive. The measurements were applied easily in theatre allowing it to be used as a routine clinical tool for confirming correct electrode placement.


Assuntos
Implante Coclear , Implantes Cocleares , Algoritmos , Cóclea/diagnóstico por imagem , Cóclea/cirurgia , Implante Coclear/métodos , Eletrodos Implantados , Humanos , Estudos Prospectivos
5.
Front Neurol ; 12: 760831, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34803893

RESUMO

Objective: To determine audiological and clinical results of cochlear implantation (CI) comparing two populations with single-sided deafness (SSD): post-lingually deaf children between 6 and 12 years of age, and post-lingually deaf adults, in order to evaluate the effect of CI in different age groups. Design: Retrospective case review. Setting: Tertiary clinic. Patients and Method: Twenty-three children and twenty-one adult patients that were candidates for CI with single-side deafness were included. In all cases we evaluate: Speech perception thresholds; disyllabic words test (65 dB SPL) were performed in the modalities S0-SCI-SNH and Auditory Lateralization Test. The Speech, Spatial, and Qualities of Hearing Scale (SSQ) questionnaire was also used. All results were obtained after 12 months of CI activation. Results: In children, the most common etiology was idiopathic sensory-neural hearing loss. They showed positive results in the Auditory Lateralization Test. In the Speech Test, word recognition in noise improved from 2% preoperatively to 61.1% at a mean follow-up of 1 year (S0 condition) in children [test with signal in CI side 60% and signal normal hearing side (plugged) 31%]. The processor was used for >12 h in all cases. With respect to the SSQ questionnaire, parents were more satisfied within the postoperative period than within the preoperative period. For adults, the most common etiology was idiopathic sudden sensorineural hearing loss (SNHL). Positive results in the Auditory Lateralization Test were found. With respect to the Speech Test in quiet conditions: Word recognition in noise improved from 5.7% preoperatively to 71.8% at a mean follow-up of 1 year [test with signal in CI side 68% and signal normal hearing side (plugged) 41%]. The processor was used for >12 h. In the SSQ questionnaire, the post-operative results showed a beneficial effect of the CI. No adverse events were reported during the study period. No differences were found between children and adults in all tests in this study. Conclusions: Cochlear implantation in post-lingually deaf adults and children with SSD can achieve a speech perception outcome comparable with CI in conventional candidates. Improvements in spatial hearing were also observed. Careful patient selection and counseling regarding potential benefits are important to optimize outcomes.

6.
J Clin Med ; 10(17)2021 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-34501410

RESUMO

BACKGROUND: The proximity of the electrode to the modiolar wall may be of interest to investigate the effect of pitch discrimination. This research establishes the relation between these factors and whether perimodiolar positions may provide benefits regarding improved electrode discrimination. METHODS: A prospective randomized study including 24 post-lingual deaf adults was performed. A psychoacoustic study was done by using a psychoacoustic research platform. Radiological study, and a cone-beam computed tomography was used to assess post cochlear implantation electrodes' position. Trans-impedance matrix (TIM) analysis was performed after cochlear implant insertion in all cases, and pupillometry test was also performed. RESULTS: 12 patients received a slim perimodiolar electrode array, and 12 patients received a straight electrode array. Although all the patients showed similar speech test results after 12 months follow-up, those implanted with a perimodiolar electrode obtained better scores in electrode discrimination test and pupillometry test, and showed more homogenous TIM patterns. CONCLUSIONS: The better positioning of the electrode array seams to provide a better hearing resolution and less listening effort trans-impedance matrix seems to be a useful tool to analyze positioning of the perimodiolar array.

7.
Front Neurol ; 12: 663803, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34113311

RESUMO

Objective: Several studies have demonstrated the possibility to obtain vestibular potentials elicited with electrical stimulation from cochlear and vestibular implants. The objective of this study is to analyze the vestibular-evoked myogenic potentials (VEMPs) obtained from patients implanted with cochlear and vestibulo-cochlear implant. Material and Methods: We compared two groups: in the first group, four cochlear implant (CI) recipients with present acoustic cVEMPs before CI surgery were included. In the second group, three patients with bilaterally absent cVEMPs and bilateral vestibular dysfunction were selected. The latter group received a unilateral cochleo-vestibular implant. We analyze the electrically elicited cVEMPs in all patients after stimulation with cochlear and vestibular electrode array stimulation. Results: We present the results obtained post-operatively in both groups. All patients (100%) with direct electrical vestibular stimulation via the vestibular electrode array had present cVEMPs. The P1 and N1 latencies were 11.33-13.6 ms and 18.3-21 ms, respectively. In CI patients, electrical cVEMPs were present only in one of the four subjects (25%) with cochlear implant ("cross") stimulation, and P1 and N1 latencies were 9.67 and 16.33, respectively. In these patients, the responses present shorter latencies than those observed acoustically. Conclusions: Electrically evoked cVEMPs can be present after cochlear and vestibular stimulation and suggest stimulation of vestibular elements, although clinical effect must be further studied.

8.
Audiol Neurootol ; 25(1-2): 35-41, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31927546

RESUMO

BACKGROUND: The peripheral vestibular end organ is considered to consist of semi-circular canals (SCC) for detection of angular accelerations and the otoliths for detection of linear accelerations. However, otoliths being phylogenetically the oldest part of the vestibular sensory organs are involved in detection of all motions. SUMMARY: This study elaborates on this property of the otolith organ, as this concept can be of importance for the currently designed vestibular implant devices. Key Message: The analysis of the evolution of the inner ear and examination of clinical examples shows the robustness of the otolith system and inhibition capacity of the SCC. The otolith system must be considered superior to the SCC system as illustrated by evolution, clinical evidence, and physical principles.


Assuntos
Membrana dos Otólitos/fisiologia , Reflexo Vestíbulo-Ocular/fisiologia , Vestíbulo do Labirinto/fisiologia , Humanos , Sáculo e Utrículo/fisiologia , Canais Semicirculares/fisiologia
9.
Audiol Neurootol ; 25(1-2): 6-24, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31533097

RESUMO

BACKGROUND: In patients with bilateral vestibulopathy, the regular treatment options, such as medication, surgery, and/or vestibular rehabilitation, do not always suffice. Therefore, the focus in this field of vestibular research shifted to electrical vestibular stimulation (EVS) and the development of a system capable of artificially restoring the vestibular function. Key Message: Currently, three approaches are being investigated: vestibular co-stimulation with a cochlear implant (CI), EVS with a vestibular implant (VI), and galvanic vestibular stimulation (GVS). All three applications show promising results but due to conceptual differences and the experimental state, a consensus on which application is the most ideal for which type of patient is still missing. SUMMARY: Vestibular co-stimulation with a CI is based on "spread of excitation," which is a phenomenon that occurs when the currents from the CI spread to the surrounding structures and stimulate them. It has been shown that CI activation can indeed result in stimulation of the vestibular structures. Therefore, the question was raised whether vestibular co-stimulation can be functionally used in patients with bilateral vestibulopathy. A more direct vestibular stimulation method can be accomplished by implantation and activation of a VI. The concept of the VI is based on the technology and principles of the CI. Different VI prototypes are currently being evaluated regarding feasibility and functionality. So far, all of them were capable of activating different types of vestibular reflexes. A third stimulation method is GVS, which requires the use of surface electrodes instead of an implanted electrode array. However, as the currents are sent through the skull from one mastoid to the other, GVS is rather unspecific. It should be mentioned though, that the reported spread of excitation in both CI and VI use also seems to induce a more unspecific stimulation. Although all three applications of EVS were shown to be effective, it has yet to be defined which option is more desirable based on applicability and efficiency. It is possible and even likely that there is a place for all three approaches, given the diversity of the patient population who serves to gain from such technologies.


Assuntos
Terapia por Estimulação Elétrica , Doenças Vestibulares/terapia , Vestíbulo do Labirinto/fisiopatologia , Implante Coclear , Eletrodos Implantados , Humanos , Reflexo Vestíbulo-Ocular/fisiologia , Doenças Vestibulares/fisiopatologia
10.
Audiol Neurootol ; 25(1-2): 79-90, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31801137

RESUMO

INTRODUCTION: Bilateral vestibulopathy is an important cause of imbalance that is misdiagnosed. The clinical management of patients with bilateral vestibular loss remains difficult as there is no clear evidence for an effective treatment. In this paper, we try to analyze the effect of chronic electrical stimulation and adaptation to electrical stimulation of the vestibular system in humans when stimulating the otolith organ with a constant pulse train to mitigate imbalance due to bilateral vestibular dysfunction (BVD). METHODS: We included 2 patients in our study with BVD according to Criteria Consensus of the Classification Committee of the Bárány Society. Both cases were implanted by using a full-band straight electrode to stimulate the otoliths organs and simultaneously for the cochlear stimulation we use a perimodiolar electrode. RESULTS: In both cases Vestibular and clinical test (video head impulse test, videonistagmography cervical vestibular evoked myogenic potentials, cVEMP and oVEMP), subjective visual vertical test, computerized dynamic posturography, dynamic gait index, Time UP and Go test and dizziness handicap index) were performed. Posture and gait metrics reveal important improvement if compare with preoperartive situation. Oscillopsia, unsteadiness, independence and quality of life improved to almost normal situation. DISCUSSION/CONCLUSION: Prosthetic implantation of the otolith organ in humans is technically feasible. Electrical stimulation might have potential effects on balance and this is stable after 1 year follow-up. This research provides new possibilities for the development of vestibular implants to improve gravito-inertial acceleration sensation, in this case by the otoliths stimulation.


Assuntos
Vestibulopatia Bilateral/terapia , Terapia por Estimulação Elétrica , Perda Auditiva Neurossensorial/terapia , Membrana dos Otólitos/fisiopatologia , Adulto , Vestibulopatia Bilateral/fisiopatologia , Marcha/fisiologia , Teste do Impulso da Cabeça , Perda Auditiva Neurossensorial/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Equilíbrio Postural/fisiologia , Qualidade de Vida , Estudos de Tempo e Movimento , Potenciais Evocados Miogênicos Vestibulares/fisiologia , Vestíbulo do Labirinto/fisiopatologia
11.
Otol Neurotol ; 40(5S Suppl 1): S10-S17, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31225817

RESUMO

INTRODUCTION: The radiological analysis following a cochlear implantation offers insight into the audiological outcomes of cochlear implant recipients. The wrapping factor (WF) is the most common radiological analysis measuring the modiolar position and depth of insertion of an electrode array. New measurements like the intracochlear position index (ICPI) or the homogeneity factor (HF) can offer more accurate information regarding the electrode's intracochlear position. We have also studied a new method to calculate the WF, by normalizing it with a new methodology (WFn). OBJECTIVES: To analyze and compare the results of the WF, ICPI, HF, and WFn obtained using a cone beam computer tomography (CBCT) with the histological analysis on temporal bone. MATERIAL: A perimodiolar electrode array (Nucleus Slim CI532) was inserted in three temporal bones. A perfect insertion was performed in the first temporal bone, according to the correct specifications. In the second specimen, a slightly over-inserted electrode was analyzed and in the third specimen a completely over-inserted electrode array was studied. METHOD: A CBCT was performed following the implantations and then, a histological analysis with slices perpendicular to the cochlea axis (modiolus). Each measurement was made 10 times by 10 experts (radiologist and otologist) with a total amount of 600 measurements (100 for each data, 3 CBCT and 3 histology). A t test statistical analysis was performed to compare the measurements between CBCT and histology. RESULTS: It was observed that the ICPI and the HF correctly identify the three different insertions. Regarding the WF no significant difference in the two over-inserted specimens was found. The ICPI was the only measurement that shows no statistical difference between the CBCT and the histology, so it was considered the most accurate method. Finally, the WF shows a statistical difference between the CBCT and the histology in all cases, indicating the poor value of the radiological method. The WFn analysis includes the modiolar wall length in the measurement. This improves the final result as it reduces the error induced by the size of the cochlea. CONCLUSION: The ICPI and the HF provide better radiological information than the WF, regarding the intracochlear position of the electrode array. The most relevant difference is that the ICPI, HF, and WFn include modiolar and lateral wall dimensions, thereby using the diameter of the cochlear duct for the analysis.


Assuntos
Implante Coclear/métodos , Implantes Cocleares , Tomografia Computadorizada de Feixe Cônico/métodos , Cirurgia Assistida por Computador/métodos , Cóclea/cirurgia , Humanos , Técnicas In Vitro , Osso Temporal/cirurgia
12.
Clin Otolaryngol ; 44(2): 138-143, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30354002

RESUMO

OBJECTIVE: To determine the audiological and clinical results of cochlear implantation in children below the age of 12 years old with congenital and acquired single-sided deafness. DESIGN: Observational, descriptive, transversal study. MAIN OUTCOME MEASURES: Speech reception thresholds, Cortical responses, Auditory Lateralization Test and SSQ questionnaire. PARTICIPANTS: Children < 12 implanted for congenital or acquired SSD. RESULTS: All the children with congenital SSD showed positive cortical responses. Positive results were obtained in the Auditory Lateralization Test for the following modalities: 0º, 45º and 90º. With respect to the Speech Test, the children with acquired SSD showed the following results: 92% and 100% in recognition and 48% and 68% (Azimuth modalities), Signal CI side 52% and 68% and Signal normal hearing side 44% - 60% (p < 0.05). In both group the processor was used for 6-12 hours. With respect to the SSQ questionnaire results, the parents were more satisfied within the post-operative period than within the pre-operative period (P<0.001). CONCLUSIONS: Cochlear implant provides children with congenital SSD with significant audiological and subjective benefits. Children with congenital SSD and implanted after a longer period may not have an important benefit (binaural) although other bilateral effects can be achieved. Children with post-lingual unilateral deafness and after a short period of hearing deprivation probably integrated the normal acoustic hearing with the cochlear implant electrical signal and showed binaural benefits.


Assuntos
Implante Coclear , Implantes Cocleares , Perda Auditiva Unilateral/etiologia , Perda Auditiva Unilateral/terapia , Perda Auditiva/congênito , Perda Auditiva/terapia , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Localização de Som , Percepção da Fala , Resultado do Tratamento
13.
Int J Numer Method Biomed Eng ; : e2992, 2018 Apr 06.
Artigo em Inglês | MEDLINE | ID: mdl-29633585

RESUMO

This paper presents a new procedure to design optimal electrodes for cochlear implants. The main objective of this study is to find a set of electrode designs that maximize the focalization and minimize the power consumption simultaneously. To achieve that, a criterion to measure the ability of focalization of an electrode is proposed. It is presented a procedure to determine (1) the electrical potential induced by an electrode by solving the Laplace equation through the finite element method; (2) the response of a neuron to an applied field using NEURON, a compartmentalized cell model; (3) the optimization to find the best electrode designs according to power consumption and focalization by 2 evolutionary multiobjective methods based on the non-dominated sorting genetic algorithm II: a straight multiobjective approach and a seeded multiobjective approach. An electrode design formed by 2 conductive rings with a possible difference of potential between them is proposed. It is analyzed that the response of the neuron is determined by the shape and the difference of the potential between the electrode rings. Our procedure successfully achieves a nondominated set of optimum electrode designs improving a standard electrode in both objectives, as designs with better focalization allow to include extra electrodes in the cochlear implant, and designs with lower power consumption extend the length of the battery.

14.
Eur Arch Otorhinolaryngol ; 275(6): 1385-1394, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29610960

RESUMO

OBJECTIVE: The aim of the present study is to evaluate the effect of electrode discrimination based on electrode to modiolus distance in different cochlear implant models, using image information to estimate the outcomes after an implantation on electrode discrimination METHODS: A descriptive prospective randomized study performed during 16 months. A psychoacoustic platform was used to evaluate patients' electrode discrimination capabilities of patients. For the acquisition of the images, a cone beam computed tomography was used to assess postcochlear implantation of electrodes' position. We considered two other new measurements: the intracochlear position index, which indicates how far is the electrode from the modiolar wall, and the homogeneity factor (HF), which provides us with information about the distance between the electrodes and the modiolus RESULTS: 21 postlingually deaf adults showing different CI models [CI522 (n = 7), CI512 (n = 7), and CI532 (n = 7)] that corresponded to the lateral and perimodiolar array electrodes. The average success rate of the CI522 group was 47%, of the CI512 group was 48%, and of the CI532 group was 77%. There is statistically significant difference between groups CI532-CI522 (p = 0.0033) and CI532-CI512 (p = 0.0027) CONCLUSION: The Nucleus CI532 offers a better perimodiolar placement. HF and IPI measurements provide information about the electrodes location inside the cochlea, being related to electrode discrimination.


Assuntos
Implante Coclear/métodos , Implantes Cocleares , Surdez/diagnóstico por imagem , Surdez/terapia , Adolescente , Adulto , Idoso , Percepção Auditiva , Cóclea/diagnóstico por imagem , Cóclea/cirurgia , Tomografia Computadorizada de Feixe Cônico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Psicoacústica , Adulto Jovem
15.
Otol Neurotol ; 38(10): e429-e437, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-29135866

RESUMO

HYPOTHESIS: Modiolar proximity of the cochlear implant electrodes and low impedance values have a positive effect on electrical pitch discrimination. BACKGROUND: The proximity of the cochlear electrode to the modiolar wall can determine changes in tissue and fluid environment. With the onset of soft-surgery techniques, the trauma caused during surgery has been reduced, minimizing fibrous growth. METHODS: Computed tomography-scan measurements of electrode-inner wall distance and psychoacoustic electrode discrimination tests were done. Neural Response Telemery and impedance data were used in the study. RESULTS: It was found that patients fitted with perimodiolar arrays have lower impedance values and smaller electrode-inner wall distances than those fitted with straight arrays. These variables were significantly correlated to electrode discrimination. It was found that a closer distance to the modiolus also results in better electrode discrimination. CONCLUSION: Perimodiolar electrodes could be a better solution in terms of pitch discrimination both because they are closer to the modiolus and because their impedance is lower.


Assuntos
Implante Coclear/métodos , Implantes Cocleares , Discriminação da Altura Tonal/fisiologia , Adulto , Cóclea/cirurgia , Impedância Elétrica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Psicoacústica , Tomografia Computadorizada por Raios X
16.
J Int Adv Otol ; 13(2): 154-161, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28816686

RESUMO

OBJECTIVE: Electrical stimulation of the utricular and saccular portions of the vestibular nerve improves stability in patients suffering from vestibular dysfunction. The main objective of this study was to evaluate a new technique, vestibular response telemetry (VRT), for measuring the electrically evoked vestibular compound action potential (saccular and utricular) after stimulating the otolith organ (saccular and utricular) in adults. This study used evidence that the otolith organ can be electrically stimulated in order to develop a new vestibular implant design to improve the sensation of gravitoinertial acceleration. MATERIALS AND METHODS: Four adult patients were evaluated by using a variety of measurement procedures with novel VRT software. VRT values were obtained by stimulating with three full-band Nucleus CI24RE (ST) electrodes. Specific stimuli were used. Simultaneously, electrical ocular vestibular evoked myogenic potentials (eoVEMPs) were recorded in the contralateral side. RESULTS: Electrically evoked compound action potentials were obtained in 10 of the 12 electrodes tested, and eoVEMPs were recorded when VRT was present. In addition to the validation of this technique, a set of default clinical test parameters was established. The VRT response morphology consisted of a biphasic waveform with an initial negative peak (N1) followed by a positive peak (P1), and latencies were typically 400 µs for N1 and 800 µs for P1. The consequences for the development of a vestibular implant for the improvement of gravitoinertial acceleration sensation are also presented. CONCLUSION: The VRT measurement technique has been shown to be a useful tool to record neural response on the otolith organ, and thus it is a convenient tool to evaluate whether the implanted electrodes provide a neural response or not. This can be used for the early development of vestibular implants to improve gravitoinertial acceleration sensation.


Assuntos
Estimulação Elétrica , Sáculo e Utrículo/fisiologia , Potenciais Evocados Miogênicos Vestibulares/fisiologia , Nervo Vestibular/fisiologia , Potenciais de Ação/fisiologia , Adulto , Feminino , Humanos , Masculino , Doença de Meniere/fisiopatologia , Pessoa de Meia-Idade , Sáculo e Utrículo/inervação , Software , Telemetria
17.
Audiol Neurootol ; 21 Suppl 1: 36-42, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27806363

RESUMO

Cochlear implantation has a significant impact on patients' social life, performance of activities, and self-esteem. The objective of this retrospective study was to assess the health-related quality of life of cochlear implant users aged under and over 60 years by a self-report using the Glasgow Health Status Inventory and the Abbreviated Profile of Hearing Aid Benefit. It was observed that quality of life values increased very rapidly straight after implantation regardless of age. Bilateral cochlear implant users showed better results in environments with background noise and in a reverberant room than unilateral cochlear implant users. Quality of life improved independently of hearing performance benefits for patients over 60 years at implantation.


Assuntos
Implante Coclear/métodos , Nível de Saúde , Qualidade de Vida , Percepção da Fala , Adolescente , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Implantes Cocleares , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ruído , Estudos Retrospectivos , Resultado do Tratamento , Adulto Jovem
18.
J Int Adv Otol ; 12(1): 1-7, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27340975

RESUMO

OBJECTIVE: Prediction of speech recognition (SR) and quality of life (QoL) outcomes after cochlear implantation is one of the most important challenges for otologists. By sifting through very large amounts of data, data mining reveals trends, patterns, and relationships that might otherwise have remained undetected. There are identifiable pre-implantational factors that condition the cochlear implantation outcome. Our objective is to design a data mining system to predict and classify cochlear implant (CI) predictable benefits in terms of SR and QoL in each patient. MATERIALS AND METHODS: This is an observational study of CI users for at least one year. Audiological benefits and its relation to QoL are analyzed using the Glasgow Benefit Inventory (GBI) and the Specific Questionnaire (SQ). Sociodemographic and medical variables are processed in SPSS Statistics 19.0, MatLab® and Weka®. Classifiers are designed using the nearest neighbour and decision tree algorithms. Estimators are created by linear logistic regression. RESULTS: A total of 29 patients (mean age, 55.3 years; 52% female and 48% male) including 48% unilateral CI users and 51% bimodal CI users were included in the study. GBI improved by 36 points and SQ by 1.7 (p<0.05). Using Nearest Neighbour (IB1) algorithm for classifiers, interesting attributes were identified for SR and SQ result classification (success rate: 80.7%). Decision tree algorithm (J48) showed influencing variables for GBI (success rate: 81%). Estimators by linear logistic regression analysis disclosed a precision of 85%, 68%, and 71% for SR, GBI, and SQ, respectively. CONCLUSION: Our study proposes a systematized system to classify and estimate SR and QoL improvement based on our initial evaluation to complement decision making and patients' information.


Assuntos
Implante Coclear/psicologia , Mineração de Dados , Surdez/psicologia , Surdez/reabilitação , Qualidade de Vida/psicologia , Teste do Limiar de Recepção da Fala , Algoritmos , Árvores de Decisões , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Prognóstico , Inquéritos e Questionários
19.
Otol Neurotol ; 36(4): 720-6, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25420082

RESUMO

HYPOTHESIS: Subjects with normal hearing (NH) experience lower performance in speech understanding in noise when frequency components of speech above 8 kHz are removed. BACKGROUND: Previous studies have explored speech perception in noise under various circumstances, but none have been specifically designed to explore the relevance of frequencies above 8 kHz and, more specifically, for the Spanish language. METHODS: Twenty-nine subjects with NH, aged 19 to 55 years, and native speakers of the Spanish language listened to two sets of three disyllabic word lists with background noise. One set of words was unfiltered and included frequency components up to 22 kHz, and another set was band-pass filtered to include frequency components between 70 Hz and 8 kHz. Words were presented at 65 dB sound pressure level. Each set of words was presented with background noise with the same bandwidth limit as the accompanying list and adjusted to construct signal-to-noise ratio (SNR) conditions of +5, 0, and -5 dB. RESULTS: Results demonstrate a higher performance for unfiltered words at +5 and -5 dB SNR, although not at 0 dB SNR. For SNR +5 dB and -5 dB, the average success rate in word recognition was 17% higher when words were not filtered. For the case SNR = 0, however, both conditions yield statistically similar results. CONCLUSION: This study suggests that high-frequency components above 8 kHz contribute to speech understanding in noise for subjects with NH of the Spanish language. Given these findings, it would be interesting to determine if bandwidth limitations in current hearing prostheses may contribute to known difficulties with perception of speech in noise in hearing-impaired subjects.


Assuntos
Ruído , Percepção da Fala/fisiologia , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Testes de Discriminação da Fala , Adulto Jovem
20.
J Int Adv Otol ; 11(3): 212-7, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26915152

RESUMO

OBJECTIVE: To evaluate 1) if air traffic controllers (ATC) perform better than non-air traffic controllers in an open-set speech-in-noise test because of their experience with radio communications, and 2) if high-frequency information (>8000 Hz) substantially improves speech-in-noise perception across populations. MATERIALS AND METHODS: The control group comprised 28 normal-hearing subjects, and the target group comprised 48 ATCs aged between 19 and 55 years who were native Spanish speakers. The hearing -in-noise abilities of the two groups were characterized under two signal conditions: 1) speech tokens and white noise sampled at 44.1 kHz (unfiltered condition) and 2) speech tokens plus white noise, each passed through a 4th order Butterworth filter with 70 and 8000 Hz low and high cutoffs (filtered condition). These tests were performed at signal-to-noise ratios of +5, 0, and -5-dB SNR. RESULTS: The ATCs outperformed the control group in all conditions. The differences were statistically significant in all cases, and the largest difference was observed under the most difficult conditions (-5 dB SNR). Overall, scores were higher when high-frequency components were not suppressed for both groups, although statistically significant differences were not observed for the control group at 0 dB SNR. CONCLUSION: The results indicate that ATCs are more capable of identifying speech in noise. This may be due to the effect of their training. On the other hand, performance seems to decrease when the high frequency components of speech are removed, regardless of training.


Assuntos
Aviação , Ruído , Exposição Ocupacional , Percepção da Fala , Adolescente , Adulto , Estudos de Casos e Controles , Humanos , Pessoa de Meia-Idade , Psicoacústica , Adulto Jovem
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